The Space will stop over the top of a 3 nucleotide portion of the mRNA - this is the codon. Ribosome threads the mRNA through it and it has these spaces that allow tRNA to fit in. Now off to the ribosome and those codons on the mRNA. An AMINO ACID gets put on the 3 hydroxyl group by an enzyme, and this becomes a CHARGED tRNA. They have really 2 important parts (don't tell an RNA researcher I said this! - i did my phd in RNA structure and they'd take it back if they read that).the anticodon loop and the 3 hydroxyl. tRNA molecules are individual molecules of mRNA. If we look at the top strand DNA sequence, we see it is: 5 -ATGCGTAGT-3.so the mRNA that gets made is the SAME sequence at the top strand!!(U instead of T) This is because the mRNA is made as a compliment of the bottom strand, and the top strand is the compliment to the bottom strand. Now, the reason we are talking about this is because the mRNA is transcribed using the bottom strand as a template!! So, the above piece of DNA would result in an mRNA (lowercase) sequence that looks something like this: The entire "DNA gets turned into mRNA" is a little bit more complicated because we have to consider the 5 to 3 direction of DNA.ĭNA has a top strand that runs 5 -3.and a complementary bottom strand that also runs 5'-3', but it runs in the opposite direction (like it got flipped around), so it is oriented in its 3 -5 direction.
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